Application

No.109
Chiral Reducing Reagents
C1615 (-)-B-Chlorodiisopinocampheyl-
borane (ca.65% in n-Hexane) (1a)
100ml
C1614 (+)-B-Chlorodiisopinocampheyl-
borane (ca.65% in n-Hexane) (1b)
100ml

References

1) Asymmetric reduction of aryl alkyl ketones and aliphatic ketones
a) H. C. Brown, J. Chandrasekharan, P. V. Ramachandran, J. Am.C hem. Soc., 110, 1539 (1988).
b) idem, J. Org. Chem., 51, 3394 (1986).
c)J. Chandrasekharan, P. V. Ramachandran,H. C. Brown, ibid., 50, 5446 (1985).
2) Asymmetric reduction of hindered acetylenic ketones
P. V. Ramachandran, A. V. Teodorovic, M. V . Rangaishenvi, H. C. Brown, J. Org. Chem., 57, 2379 (1992).
3) Asymmetric reduction of fluoro ketones
P. V. Ramachandran, A. V. Teodorovic, H. C. Brown, Tetrahedron, 49, 1725 (1993).
4) Asymmetric reduction of acylsilanes
J. D. Buynak, J. B. Strickland, T. Hurd, A. Phan, J. Chem. Soc., Chem. Commun., 1989, 89.
5) A highly enantioselective synthesis of both optical isomers of the antidepressant drugs
M. Srebnic, P. V. Ramachandran, H. C. Brown, J. Org. Chem., 53, 2916 (1988).
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